Friday, May 13

Muscle Biology

8:30-8:45

Welcome

President Richard McCullough

8:45-9:00

Introduction

Scott Stagg

9:00-9:30

Helical Polymers: The Surprises Continue

Ed Egelman

9:30-10:00

Why is the thin filament important for thick filament function? 

Jose Pinto

10:00-10:30

Ken Taylor and the myosin interacting-heads motif 

Raúl Padrón

10:30-10:45

Break /Group photo

10:45-11:15

That muscular question has been bugging me: Can we really untangle the thick and thin of it? 

Bryant Chase

11:15-11:45

Three-dimensional structure of vertebrate muscle Z-band

Pradeep Luther

11:45-12:00

Reaching higher and higher with JEOL’s CRYO ARM

Jaap Brink, JEOL

12:00-1:00

Lunch

Friday, May 13

Single Particle Cryo-EM

1:00-1:30

Visualizing cryoEM structures beyond expectations

Wah Chiu

1:30-2:00

CryoEM Structures of Pseudouridine-free Ribosome Suggest Impacts of Chemical Modifications on Ribosome Conformations 

Hong Li

2:00-2:30

Detection of distinct 60S ribosome maturation intermediates in cells by 2D template matching

Niko Grigorieff

2:30-3:00

Determining the structures of challenging membrane remodeling complexes   

Scott Stagg

3:00-3:15

Break 

3:15-3:45

AAGAB chaperones step-wise assembly of adaptor complexes

Qian Yin 

3:45-4:15

AAV and the circle of life 

Michael Chapman

4:15-5:00

Keynote Address - My 27 years of cryoEM and Structural Biology research at Florida State University

Ken Taylor

Saturday, May 14

Taylor Alumni and Collaborators

8:30-8:40

Introduction

Beth Stroupe

8:40-9:00

Remembrances of Don Caspar

Michael Chapman

9:00-9:30

Structural snapshots of TRPV1 in response to stimuli

Yifan Cheng

9:30-10:00

Visualizing a reversible rotary motor in action

Jun Liu

10:00-10:30

Myosin coiled-coil in its native environment 

Hamidreza Ramani

10:30-10:45

Break 

10:45-11:15

Cryo-EM: A Computer Scientist's Perspective 

Chaity Banerjee

11:15-11:30

The Cryo-EM structure of the flight muscle thick filament from the Bumble Bee, Bombus ignitius, at 6 Å Resolution 

Jiawei Li

11:30-11:45

CryoEM studies on F-actin decorated with smooth muscle heavy meromyosin 

Alimohammad Hojjatian

11:45-12:00

Advances in Electron Microscopy for the Life Sciences

Natalia de Val, Thermo Fisher Scientific

12:00-1:00

Lunch

Saturday, May 14

Structural Biology and Hybrid Methods

1:00-1:30

Roles of shared structural modules in large human transcription complexes

Eva Nogales

1:30-2:00

Development of fluorescence probes to visualize HIV-1 disassembly in situ, by correlative light and CryoEM 

Ashwanth Francis

2:00-2:15

Break

2:15-2:45

When cryo-EM gives you lemons, use small angle scattering   

Beth Stroupe

2:45-3:15

Ultra-Fast Optical Trapping Reveals MechanoChemical Steps in Cardiac Muscle and Myopathies 

Yale Goldman

3:15-3:45

Protein Functional Motion as Revealed by Long-Timescale Atomistic Simulation

Wei Yang 

3:45-4:00

Closing statements